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Physicians who treat opioid addiction also have the option of utilizing 'medication-assisted treatment', along with the most common medications employed in the treatment of opioid dependence today are methadone, naltrexone, and buprenorphine (Suboxone). Using two separate drugs to lose weight can be very effective you can find combinations before the FDA now awaiting approval. When dealing with weight reduction and the those who go through it one should err to the side of caution and let the FDA do its job and demand some study be done so that the public is aware of the side effects and dangers of the medications before we take them. Keep in mind that drug companies have been in business to generate income and that they would say everything to keep people on their medications. Researchers discovered that participants using this drug to get a year, lost excess weight within one month and have kept the extra weight off during the entire 56 weeks in the study. Contrave is often a combination with the drugs naltrexone and bupropion, which usually reflect a fresh trend of weight-loss drugs which are made up of several active ingredient, which might make them more potent and safer. Combo-pilling is the newest fad or even better the newest in the future under scrutiny and therefore it is just more publicly known in recent months, comb-pilling for weight reduction has been around since the eighties. The biggest reason that utilizing a combination of pills is starting to become popular could be the fact that by right now there are no long term prescription slimming capsules that have been licensed by the FDA besides orlistat. The truly disturbing part is doctors are prescribing these combinations of medications although some people might of the combinations are actually rejected or have yet to be approved by the FDA. Seizures certainly are a side effect with Contrave and really should not be taken in people with seizure disorders. The drug could also raise blood pressure and heart rate, and mustn't be used in individuals with a history of heart attack or stroke in the previous six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy while using drug. The FDA also warned that Contrave can raise blood pressure and pulse rate and must 't be used in patients with uncontrolled high blood pressure level, and also by you are not heart-related and cerebrovascular (circulation system dysfunction impacting your brain) disease. Patients using a history of heart attack or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes using a boxed warning to alert health care professionals and patients for the increased chance of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for smoking cessation. "There were no warning signs of depression or suicidal thoughts in trial participants," said Fujioka.